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Showing 1 to 12 of 213 entries
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Dual Transmembrane Signalling Mechanisms in Eosinophils: Evidence for Two Functionally Distinct Receptors for Platelet-Activating Factor.

International archives of allergy and immunology

Kroegel C, Warner JA, Giembycz MA, Matthys H, Lichtenstein LM, Barnes PJ.
PMID: 34167200
Int Arch Allergy Immunol. 1992;99(2):226-229. doi: 10.1159/000236253. Epub 2009 Sep 02.

The effect of PAF on eosinophil activation was investigated. TxB2 release required a lower concentration of PAF (ED50 = 17.2 nM) whereas for superoxide anion (O2) production doses in excess of 1 μM (ED50 = 31.7 μM) were needed....

Regulation of Mast Cell Proliferation, Maturation and Function by Stem Cell Factor, a Ligand for the c-kit Receptor.

International archives of allergy and immunology

Galli SJ, Tsai M, Wershil BK.
PMID: 34167206
Int Arch Allergy Immunol. 1992;99(2):234-237. doi: 10.1159/000236255. Epub 2009 Sep 02.

Mast cell development in mice is critically regulated by stem cell factor (SCF), a product of fibroblasts and other cell types which is a ligand for the tyrosine kinase receptor protein encoded by the proto-oncogene c-kit. In mice, recombinant...

Human Lung Mast Cell and Alveolar Macrophage Cytoplasmic Lipid Bodies Contain Arachidonic Acid and Prostaglandin Endoperoxide Synthase (Cyclooxygenase), the Substrate and Enzyme Necessary for Prostaglandin Production.

International archives of allergy and immunology

Dvorak AM, Schleimer RP, Dvorak HE, Lichtenstein LM, Weller PF.
PMID: 34167207
Int Arch Allergy Immunol. 1992;99(2):208-217. doi: 10.1159/000236250. Epub 2009 Sep 02.

Lipid bodies are non-membrane-bound cytoplasmic organelles that are prevalent in mammalian cells of diverse lineages and that have been observed to increase in cells involved in inflammatory responses. Specialized morphological and biochemical studies have provided evidence for the involvement...

Microenvironmental Control of Inflammatory Cell Differentiation.

International archives of allergy and immunology

Denburg J, Dolovich J, Kanai N, Finotto S, Ohno I, Marshall J, Jordana M.
PMID: 34167219
Int Arch Allergy Immunol. 1992;99(2):330-332. doi: 10.1159/000236276. Epub 2009 Sep 02.

A wide body of information now exists on hemopoietic and proinflammatory cytokine production by structural cells of the microenvironment. Included among these are epithelial cells, endothelial cells and fibroblasts which can, either constitutively or upon stimulation with other cytokines...

IL-3 Primes and Evokes Histamine Release from Human Basophils but not Mast Cells.

International archives of allergy and immunology

Okayama Y, Church MK.
PMID: 34167220
Int Arch Allergy Immunol. 1992;99(2):343-345. doi: 10.1159/000236280. Epub 2009 Sep 02.

To assess the effect of IL-3 on mediator release from human histamine-containing cells, we have investigated IL-3 induced histamine release (HR) and IL-3 priming of IgE-dependent and IgE-independent HR from human basophils and mast cells dispersed from human skin,...

Therapeutic Potential of Recombinant Allergens.

International archives of allergy and immunology

Mohapatra SS, Sehon AH.
PMID: 34167221
Int Arch Allergy Immunol. 1992;99(2):265-270. doi: 10.1159/000236262. Epub 2009 Sep 02.

The application of molecular biology in recent years to the characterization of protein allergens has led to spectacular advances in the synthesis of cDNAs of several major allergens and in the determination of their primary structures. This information has...

Effect of the c-kit Ligand on Mediator Release by Human Lung Mast Cells.

International archives of allergy and immunology

Bischoff SC, Dahinden CA.
PMID: 34167226
Int Arch Allergy Immunol. 1992;99(2):319-322. doi: 10.1159/000236273. Epub 2009 Sep 02.

IgE-independent mediator release or modulation of mediator release by cytokines has not been described for human lung mast cells (MC) so far. We recently showed that among a large number of cytokines examined the c-kit ligand (KL) is a...

Homology of Two cDNAs Coding for Birch Pollen Allergens with Calmodulin: Protein-Bound Ca2+ Affects the IgE-Binding Capacity.

International archives of allergy and immunology

Seiberler S, Scheiner O, Kraft D, Valenta R.
PMID: 34167227
Int Arch Allergy Immunol. 1992;99(2):380-381. doi: 10.1159/000236290. Epub 2009 Sep 02.

Birch pollen is known to contain two well-defined allergens, Bet v I, a protein, which is a major allergen for 95% of the birch-pollen-allergic individuals, and birch profilin, which we could identify as a novel type of plant pan...

Profilin, a Novel Plant Pan-Allergen.

International archives of allergy and immunology

Valenta R, Duchêne M, Vrtala S, Valent P, Sillaber C, Ferreira F, Tejkl M, Hirschwehr R, Ebner C, Kraft D, Scheiner O.
PMID: 34167231
Int Arch Allergy Immunol. 1992;99(2):271-273. doi: 10.1159/000236263. Epub 2009 Sep 02.

Recently we identified birch profilin as a novel pollen allergen which showed significant sequence homology with profilins from different eukaryotic organisms. Profilins were described to control actin polymerization and to participate in signal transduction via the phosphoinosite pathway, but...

Immunochemical Analysis of the Specificites of IgE Antibodies Directed to Benzylpenicilloyl.

International archives of allergy and immunology

Blanca M, Moreno F, Mayorga C, Perez E, Fernandez J, Terrados S, Vega JM, Torres MJ, Juarez C, García J.
PMID: 34167247
Int Arch Allergy Immunol. 1992;99(2):439-442. doi: 10.1159/000236306. Epub 2009 Sep 02.

The contribution that the different parts of the benzylpenicillin (BP) molecule made to the antigen-binding site was studied using human IgE sera specific to the benzylpenicilloyl (BPO) determinant. Radioallergosorbent test inhibition studies were made using in the solid phase...

Changes in Histamine/Tryptase Levels in Skin Chambers: Application for Clinical Evaluation of Atopic Dermatitis.

International archives of allergy and immunology

Tsubaki T, Iikura Y, Saito H, Akasawa A, Tabana T, Matsuda S, Koshibu T, Iwasaki A, Obata T, Sugihara Y.
PMID: 34167249
Int Arch Allergy Immunol. 1992;99(2):459-462. doi: 10.1159/000236312. Epub 2009 Sep 02.

We measured changes in histamine and tryptase levels in fluid of children with atopic dermatitis using skin chamber methods and evaluated the correlation with clinical symptoms. Skin chambers were applied to forearm skin which had been scratched with a...

Immunological Parameters in the Immunotherapy Follow-Up.

International archives of allergy and immunology

Oehling A, Sanz ML, García BE.
PMID: 34167256
Int Arch Allergy Immunol. 1992;99(2):474-477. doi: 10.1159/000236317. Epub 2009 Sep 02.

The purpose of our study was to evaluate the effect of immunotherapy on the levels of antigen-specific IgG4. We studied a group of 35 asthmatic patients with sensitization to Dermatophagoides pteronyssinus and a group of 226 pollinic patients with...

Showing 1 to 12 of 213 entries